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Preclinical studies demonstrate that QA disrupts mitochondrial ATP production following intrastriatal administration, although it remains unclear whether this arises from direct mitochondrial toxicity or occurs secondary to ROS generation following NMDAR overstimulation [140, 141]
Rights and permissions About this article Cite this article Yoshida, H., Hara, K.Y., Kiriyama, K
[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Matsumoto Y, et al
A zebrafish study demonstrated that AGAT and GAMT were broadly expressed in multiple tissues (central nervous system, liver, and pancreas) in the same pattern as the homologous genes expressed in mammal tissues [30]
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