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Tirzepatides dual-action mechanism may provide better metabolic benefits than Semaglutide

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Full reimbursement is likely to be unaffordable for most publicly funded healthcare systems in the short term, but a steady reduction in the threshold for reimbursement is believed to be inevitable in the medium to long term

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Diabetologia 61(9):19231934

The data shows that semaglutide at the full weight loss dose has somewhat higher rates of nausea and vomiting compared to tirzepatide, though the comparison between semaglutide and tirzepatide side effects involves many variables beyond simple percentage comparisons