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A 0.41.0% reduction in HbA1c (glycosylated hemoglobin A1c) has been observed with monotherapy of alogliptin after 26 weeks of treatment [7]

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Research has shown that signal transduction involving brain-derived neurotrophic factor (BDNF) plays a crucial role in synaptic plasticity in depression, and the downregulation of BDNF may contribute to neurotoxic effects (SHKUNDIN and HALARIS, 2023)

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