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Although these studies primarily focus on safety and tolerability, they also provide the first human data on pharmacokinetics and, early pharmacodynamic (biomarker)effects

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Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family

G-proteins then lead to the inhibition of adenylate cyclase and subsequently the reduction of cAMP production [35, 36]

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