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In two trials ( n = 3697) metformin (1000 mg/day metformin) combined with pioglitazone for 3 months improved SHBG, AMH, inflammatory markers (IL6 and IL8) and postprandial glucose levels, and reduced insulin resistance compared with metformin alone, while maintaining stable weight
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TABLE 1 Metabolites relieves acetaminophen-induced liver injury
J Cereb Blood Flow Metab 26:821835 Scafidi S, OBrien J, Hopkins I, Robertson C, Fiskum G, McKenna M (2009) Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats
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