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These are (in alphabetical order): Angioedema (an allergy that causes swelling under the surface of the skin) Hypoglycemia (too low blood sugar) Increased risk of medullary thyroid cancer (not known to cause this issue in humans, only in animal studies) Pancreatitis (inflammation of the pancreas) Severe allergic reactions Stomach paralysis (the medical term is gastroparesis, which is when the muscles of your digestive system struggle to move food through your GI tract) Vision changes Make sure to go over your complete health history with your provider before starting Ozempic to see if youre at a higher risk for any of these serious side effects