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Mean T1/2 was 138.4 minutes for GLP-1 RA vs 95.0 minutes for placebo, with a pooled mean difference of 36.0 minutes (p 0.05)

The GLP-1RAs-associated weight loss is thought to be achieved through a variety of mechanisms, including the delayed gastric emptying, increased satiety, increased resting energy expenditure, as well as the direct influence of the appetite center of the brain (175)

& Zhang, J

As researchers continue to study what is GLP-1 and how does it work, new insights are emerging about its broader role in brain health, cardiovascular function, and long-term metabolic resilience

Concerns about facial volume loss, often referred to as Ozempic face, also come up

Currently, however, the majority of patients 79 percent, according to KFF are prescribed GLP-1RA medications by their primary care doctor or a specialist