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Pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate

4.3 Controversies, open questions, and future directions Despite the promising role of VNS in modulating PD via the MGBA, several controversies and unresolved issues warrant attention

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They also play a role in maintaining physiological homeostasis, such as cognition, blood pressure, feeding behavior, water balance, glucose metabolism, pain, and response to stress [7]