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Further in vitro experiments confirmed that Panobinostat, within the low nanomolar concentration range (0.555.00 nM), selectively inhibited B cell proliferation and differentiation

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GST non-enzymatic functions GSTs are also implicated as modulators of signal transduction pathways implicated in cell survival and apoptosis, where they control the activity of members of the mitogen-activated protein kinase (MAPK) family 24,25

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