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In addition, IHC staining demonstrated that the intensity of 4-HNE, reflecting the lipid perioxidation, was higher after FA injection, while LA supplementation significantly downregulated the intensity of 4-HNE

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Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization (in Eng)

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Future studies should further investigate this downstream antioxidant program to better clarify the involvement of glutathione metabolism in MAPKAPK2-mediated regulation of the KEAP1/Nrf2 pathway

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