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Genetic mutations in PINK1 and PARKIN, which regulate mitophagy, impair the clearance of damaged mitochondria, exacerbating oxidative stress (Franco et al., 2021

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10.1371/journal.pone.0232630 PLoS One

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Ann N Y Acad Sci 1053:153161 Zaitone SA, Abo-Elmatty DM, Shaalan AA (2012) Acetyl-l-carnitine and alpha-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinsons disease therapy