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This highlights the robustness of the base case results, even in the face of potential list pricing shifts

Although the weight loss is considered clinically significant according to the clinical expert consulted by CADTH on this review, there is no clear evidence that this weight loss reduces the number of patients who may develop various weight-related comorbidities, including type 2 diabetes, cardiovascular disease, and osteoarthritis

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Many have asked about nausea

Zinc has been shown to inhibit 5-reductase, which converts testosterone to its more biologically active form, DHT, which may lower some of the hyperandrogenism signs and symptoms, e.g., hirsutism