All the patients were seen at least eight years after the cancer treatment, which consisted of a combination of radiotherapy and chemotherapy with or without the use of cisplatin (CDDP)
In addition, it is known that GLP-1 signaling has anti-atherosclerotic effects in vascular smooth muscle cells 13,14,15,16
Clear evidence-based candidates: People with obesity (BMI criteria plus comorbidities) People with type 2 diabetes Those with established high cardiovascular risk People with obstructive sleep apnea and obesity Those with metabolic-associated fatty liver disease Grey zone physician-guided, case by case: Prediabetes with strong family history Metabolic syndrome Significant compulsive eating patterns or food noise Alcohol use disorder very early evidence, not yet standard of care Not currently supported by evidence: Metabolically healthy individuals seeking optimisation or longevity Routine preventative use in low-risk populations That last category is where social media is running well ahead of the data
Ghiyam says, but the compound wont have the same effect, and so depending on what it degrades into, it can introduce impurities that cause harm
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