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GLP-1 receptor agonist users had a significantly lower risk of all-cause mortality at both one year (hazard ratio [HR] 0.29) and two years (HR 0.36)

Given the chronic, fluctuating course of both BD and MetS, TPE delivered through a sustained, multidisciplinary framework, incorporating psychiatry, nutrition, behavioral therapy, and primary care, enables patients to become active, informed partners in their health

The JAHA meta-analysis showed that DVT risk increases with duration beyond 1.5 years, suggesting a time-dependent relationship that shorter trials might underestimate

Both are MHRA-approved, supported by large Phase 3 clinical trials, and available on prescription in the UK

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On the right, the cellular driver is revealed: an imbalance of immune cells, where a predominance of 'M2' macrophages triggers "woody" fibrotic tissue changes that obstruct natural fluid drainage and drive abnormal, disproportionate fat expansion