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Cystine transporters A number of cystine transporters have been described and studied in the context of cancer

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An analysis of the free energy minima and maxima for the water probe in subpockets A-C using SZMAP 37 and WaterOrientation extension in VIDA 40 is shown in Fig

Upon activation by conditions inducing ER stress, CHAC1 expression is upregulated primarily through the PERK-eIF2-ATF3/4 signaling pathway, independent of other UPR branches like IRE1-XBP1

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