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26,29,30,31 Acute precipitated withdrawal In Experiment 1, to establish the model and validate the behavioral scoring, pups were randomized within litter to receive either naloxone hydrochloride (1 mg/kg, intraperitoneal (i.p.)), a dose that has been shown to precipitate acute withdrawal in rats, 26,29,30,31 or an equal volume of saline

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These differences in affinity of APx and CAT suggest that APx is responsible for the fine tuning of ROS concentrations for signaling, whereas CAT might remove the excess ROS as was suggested after metal exposure in Arabidopsis thaliana [90]

& Molinari, C

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