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[] In one RCT involving patients on intermittent androgen deprivation (IAD) after metastatic disease, participants took curcuminoid capsules daily in the amount of 1440 mg for 6 months (ClinicalTrials.gov Identifier: NCT03211104)

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On the other hand, talin knockdown promotes negative durotaxis of MDA-MB-231 cells by suppressing adhesion reinforcement, which is observed on ~ 20 kPa substrates [96]

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