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The expression of Kiss1 and Gnrh was also lower in these mice compared to controls, and inhibition of 5 reductase-1 reduced Kiss1 and Gnrh mRNA levels and blocked GnRH release in GnRH neuronal cell cultures

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Under the direction of the authors, medical writing and editorial support were provided by Carl V

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Reducing the level of pro-inflammatory cytokines can attenuate the inflammatory response at the skin lesions of psoriasis mice, which in turn improves the symptoms of skin lesions (Wang et al., 2023)