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Research indicates it may interact with mechanisms that regulate telomerase expression

[DOI] [PubMed] [Google Scholar] 228.Sousa Silva M., Gomes R.A., Ferreira A.E., Ponces Freire A., Cordeiro C

Common gastrointestinal side effects include: Nausea (1222% of patients, dose-dependent) Diarrhea (1316% of patients) Vomiting (69% of patients) Constipation (67% of patients) Abdominal pain or discomfort (69% of patients) Decreased appetite (59% of patients) These effects are generally mild to moderate in severity and most pronounced during dose escalation

This selectivity profile makes Ipamorelin invaluable for research requiring isolated study of GH pathway effects without confounding hormonal variables

Turanli et al., 2021)