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The FGF19 family consists of FGF19, FGF21, and FGF23
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(2) EGCG induces M1 polarization via various signaling pathways including TLR4/NF-B, JAK2/STAT3, TLR2, TLR4, JNK/P38, thereby suppressing the activation of inflammatory vesicles and reducing microglial inflammation and neurotoxicity (13)
Research on IGF-1 receptor dynamics shows that receptor density decreases by approximately 40-60% after 6 weeks of continuous supraphysiological IGF-1 exposure (Yakar et al., 2002)
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