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TNF- activates heparanase and MMPs to degrade proteoglycans such as SDC-1 [71]

That tells you everything

D.MartensL.SaeysY.De PrijckS.et al (2016)

At steady state, a KEAP-1 deficiency based persistent activation of NRF2 reduced HSC quiescence without affecting their numbers

In women with diabetes, the use of MHT lowers the level of fasting blood glucose by an average of about 30%, while improving the values of lipids and blood pressure

Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women

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