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The delicate skin around your eyes is one of the first areas to show signs of fatigue, stress, and aging

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It is one of the fastest ways to fight fatigue without relying on caffeine or stimulants

This conclusion requires validation in future studies with a larger sample size

This response is partially mediated by CGRP and/or CSD, and involves oxidative stress, mitochondrial dysfunction, the assembly of NLRP3 inflammasomes, activation of microglia, and the reactivity of astrocytes

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