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PEAs documented anti-inflammatory, analgesic, antimicrobial, immunomodulatory, and neuroprotective effects make it a versatile ingredient with broad therapeutic applications

Yki-Jrvinen, H., Fatty liver: a novel component of the metabolic syndrome

While peptides are generally well-tolerated, individual responses can vary

In the current study, the estimated measured levels of APAP were indicative of reaching toxicity levels, as previously reported by The present data based on APAP-induced hepatotoxicity in mice identified that PA treatment for 7 days at a dose of 200 mg/kg/day has critical actions in modulating APAP-induced liver toxicity in mice

Despite great advances in the mechanistic understanding of inherited channelopathies, translation of mechanism-based novel therapies into clinical use remains challenging due to problems in designing and funding clinical studies with sufficient power in these rare diseases, particularly for second use applications of already approved drugs

Proceedings of the National Academy of Sciences, 2008