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Check out the GLP assessment too, I'm just in the process of updating it!

An activation reaction (phase I) is followed by a conjugation (phase II) with hydrophilic molecules like glutathione or glucose

These results demonstrate that certain patient characteristics will influence the response to treatment with specific drugs indicating the ability to target drug therapy for the specific patient

Renal and hepatic effects: Long-term or high-dose use has been associated in case reports with adverse effects on kidney and liver function

If this is unsuccessful, then adenosine should be administered intravenously

Rhonda: So thats-thats kind of the-the those adaptations that occur