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Mitochondrial activity is restored, as evidenced by improvement in the NAD/NADH ratio and sirtuin 1 activity in cardiac cells, and the inflammatory response, notably the NF-B pathway, is inhibited [16, 17]

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11 An increased concentration of TRX-1 had a positive effect on the activity of other antioxidants such as manganese superoxide dismutase and GSH peroxidase