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[478] We explained in the proposed rule that we believe aligning the NPI across the HPT and TiC MRFs would support improved cross-comparison among hospital data and health plan data, providing users of both MRFs further context about hospital standard charges

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Pre-filling syringes reduces effective dose by 58% over 24 hours due to peptide adhesion to syringe walls, which compounds across multi-day protocols and undermines dosing consistency

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Lastly, some viral diseases such as HIV or Hepatitis B can be transmitted through breastmilk and women with those diseases are advised against breastfeeding