Formation of aggregates: In injectables, peptides may clump together into aggregates, which can block needles or cause local irritation at the injection site
The most common include constipation, diarrhea, nausea, vomiting, and stomach pain
Semaglutide is administered as a convenient, once-weekly injection, which many of our patients at Centra Internal Medicine find preferable to daily oral medications
Because peptides have a complex structure, drug developers need raw materials that have consistent analytical profiles and reliable manufacturing controls
Why do GLP-1 medications cause muscle loss
Patients should be aware that some products sold as semaglutide may not contain the same active ingredient as FDA-approved semaglutide products, the agency wrote in January 2024