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PMID: 16123364

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Cormio L, Zucchi A, Lorusso F, Selvaggio O, Fioretti F, Porena M, et al

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In fact, the Wegovy and Saxenda trials mentioned in the introduction of this article display the weight-loss effects of these drugs coupled with lifestyle interventions such as a reduced- calorie diet and increased physical activity

Men saw their average weight drop from 223 pounds (101 kg) to 193 pounds (88 kg), a 13% reduction