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Abstract Based on recent retrospective, prospective, and experimental studies, mild to moderate elevation of fasting or postmethionine-load plasma homocysteine is accepted as an independent risk factor for cardiovascular disease and thrombosis in both men and women

[DOI] [PubMed] [Google Scholar] 72.Hung C.C., Ho J.L., Chang W.L., Tai J.J., Hsieh T.J., Hsieh Y.W., Hsieh Y.W., Liou H.H

Elevated redox stress has been closely associated with a variety of clinical complications, including metabolic syndrome, pulmonary dysfunction, cardiovascular disease, and neurological disorders, all of which are commonly reported in both severe COVID-19 and PCC 26

doi: 10.1038/s41477-018-0287-6 22 IchinoT.FujiK.UedaH.TakahashiH.KoumotoY.TakagiJ.et al

However, the addition of glycerol, sucrose and other polyhydric alcohols increases the stability of the protein by helping in protein folding [29]

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