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At the starting dose, a single vial lasts approximately 10 weeks

Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which mimic the action of the naturally occurring hormone GLP-1 produced in the intestines

Key Safety Findings: 12.3% placebo-adjusted weight loss at 28 weeks Discontinuation rate: ~10% (predominantly GI-related) Adverse events: Mild-moderate nausea and diarrhea (consistent with GLP-1 class) Zero severe diarrhea cases reported No new safety signals vs

Nonetheless, the financial burden obesity places on healthcare systems is significant

Neither issue is a deal-breaker, but both are worth knowing about before signing up

Shor R et al