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Compared with the initiation of sulfonylurea, the addition of SGLT2is to GLP-1RA therapy was associated with a significantly lower incidence rate of the composite cardiovascular endpoint (9.9 versus 13.0 per 1,000 person-years

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This data shows that users in clinical trials lost more weight than real-world users when taking GLP-1 medications

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While a small proportion of participants maintained their weight loss, researchers say it's still unclear what distinguishes those individuals

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