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To minimize any discomfort, practitioners often apply a topical numbing cream or use injectables that contain lidocaine, a mild anesthetic, to make the procedure more comfortable

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For patients who experience a sustained increase in resting heart rate while taking semaglutide, the drug should be discontinued

AOD9604 was first synthesized in the 1990s and is supplied as a white to off-white lyophilized (freeze-dried) powder that is readily soluble in water

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Research protocols typically use 250 to 500 mcg administered subcutaneously once or twice daily for 4 to 8 weeks