If lots of people start microdosing, it could re-trigger a GLP-1 shortage and make it harder for people with diabetes to access the medication
Both Mounjaro and Zepbound injector pens and Zepbound single-dose vials don't contain preservatives and are approved for single-use only, so dose-splitting or microdosing is not contemplated by the FDA-label, the company notes
The term has been popularized by direct-to-consumer companies that sell compounded products that are not FDA-approved GLP-1 therapies, at doses that are not based on legitimate, rigorous clinical studies
GLP-1 drugs have revolutionized the way we treat Type 2 diabetes and obesity
This concept of microdosing GLP-1s gained traction due to obesity drug shortages shortly after these new, highly effective medications were approved in 2021 and 2022
8 Surprising Health Benefits of GLP-1 Agonists Beyond Weight Loss .