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Main text Role of oxidative stress in ALS ALS is an adult-onset neurodegenerative disease, characterized by degeneration and loss of upper motor neurons (MNs) in the cerebral cortex and lower MNs in the brainstem and spinal cord [69], leading to progressive weakness of voluntary muscles, and death caused by a diaphragmatic failure within 25 years [70, 71]
It has replaced dimercaprol in the treatment of acute arsenic poisoning
After that, a melting curve analysis was performed with the following steps: 95 C for 15 s, 60 C for 60 s, and 95 C for 15 s
O'Brien ML, Vulevic B, Freer S, Boyd J, Shen H and Tew KD
In autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis, chronic inflammation and oxidative stress can damage tissues and interfere with immune tolerance