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Efficacy of vitamin C supplementation on collagen synthesis and oxidative stress after musculoskeletal injuries: a systematic review

2024 Sep-Oct 01;31(5):e619-e622

GSH synthesis is primarily regulated by GCLC activity, cysteine availability, and feedback inhibition by GSH itself

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Diacylglycerol and ceramide accumulation Consistent with the above studies, elevated plasma fatty acid concentrations can result in increased intracellular diacylglycerol (DAG) levels, leading to the activation of protein kinase C isoform (PKC-) and PKC- isoforms in skeletal muscles and liver respectively