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Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses

253,254,255 OxLDL interacts with various receptors, such as lectin-like oxidized LDL receptor-1 (LOX-1), TLR4, and RAGE, activating inflammatory pathways and increasing ROS accumulation

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These damages disrupt the integrity of the genetic code and inheritance for the mitochondrial and nuclear genomes

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