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For individuals with visceral adiposity related to specific medical conditions, specialist referral is the appropriate pathway rather than self-directed use of unlicensed agents

Animal studies show promising results for reversing signs of aging at the molecular and functional levels

However, berberine did improve blood sugar and cholesterol numbers

These include: Nausea Vomiting Diarrhoea Constipation Decreased appetite (which, whilst therapeutically intended, can occasionally be excessive) Injection-site reactions (such as redness, bruising, or discomfort at the injection site) These effects were generally mild to moderate in severity and most frequently occurred during the dose-escalation phase of treatment, tending to diminish over time

Some of it is muscle, and eating much less means taking in fewer vitamins and minerals

Hernandez et al., 2018