Metformin, an old drug for the treatment of diabetes, has been used off-label for weight control, but Amiji says its not clear whether the modest weight loss associated with the medication is due to the drug or lifestyle changes
A 2004 study looked at 481 men evaluated in an infertility clinic and found that 31 percent of them were taking alternative medications, and that 17 percent of these supplements had clear hormonal activity that was potentially detrimental to sperm production
Products with the ingredient can be used daily, as part of a morning or nighttime routine
Newer studies also suggest that zinc may regenerate thymic function, which is essential for restoring immune resilience in stressed individuals
The 2024 Yang paper in Journal for ImmunoTherapy of Cancer documented NNMT in cancer-associated fibroblasts driving tumour progression (PMID 39067875)
in the early 1990s, it is notable for stability in gastric acid, enabling rare oral bioavailability among research peptides