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Arora S, Vedpal, Chauhan N

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Takeaways Restless legs syndrome is both a sleep disorder and a movement disorder that can bring you plenty of discomfort, especially at night

Comparative example 1 Referring to the method disclosed in patent CN111378028a, the reaction formula is shown below, the main difference is that the side chain of compound 1 has no protecting group, and the other conditions are the same as in example 1

The FDA approved the Wegovy pill in December 2025, the first once-daily oral GLP-1 approved for weight loss in adults, launching in the US in January 2026