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But, if you are sweating heavily (or experiencing gut symptoms like diarrhea), supplementing with electrolytes for fasting on GLP-1 agonists is especially important, as semaglutide can increase the risk of dehydration due to nausea or low food volume

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The modest increases in response rate observed later in treatment were unexpected and may reflect enhanced task engagement following extended sucrose deprivation during the testing phase, when daily training and sucrose access were paused, rather than drug-induced activation