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She explained that only doctors with a valid Annual Practising Certificate can purchase the product directly from pharmaceutical companies, and the injections are meant to be administered by medical professionals

This can be an important consideration as one could argue that patients taking GLP-1RAs might differ, compared with patients not on these medications, in their likelihood to have seen an eye care clinician. The commentary encouraged others to take a critical look at the designs and database limitations to understand how confounding, bias and chance may explain discrepancies in studies that rely on large databases