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Excessive pro-inflammatory cytokines suppress the negative feedback of the HPA axis, boost the permeability of the blood-brain barrier, decrease the synthesis of neurotransmitters such as serotonin (5-HT), and ultimately lead to the onset of depression (Haroon and Miller, 2017

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Allow the area to air dry completely for 30 secondsinjecting into wet skin can dilute the medication and reduce effectiveness

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