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In GD, the major autoantigen (thyroid-stimulating hormone (TSH)-antibody) is to the receptor for the TSH, which causes overproduction of thyroid hormones, resulting in symptoms such as irritability, rapid heartbeat, weight loss, poor tolerance of heat and bulging eyes (Graves orbitopathy) ( Reference Effraimidis and Wiersinga 4 , Reference Marcocci, Kahaly and Krassas 7 , Reference Brent 8 )

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doi: 10.1002/ijc.22697

Appl Microbiol Biotechnol 36:538840 Awano N, Wada M, Kohdoh A, Oikawa T, Takagi H, Nakamori S (2003) Effect of cysteine desulfhydrase gene disruption on l-cysteine overproduction in Escherichia coli

doi: 10.1038/s41392-024-01772-w 36 KangYPMockabee-MaciasAJiangCFalzoneAPrieto-FariguaNStoneEet al

These mechanisms may support musculoskeletal repair, gastrointestinal healing, and reduced systemic inflammation, although results differ from person to person