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These combined actions result in decreased levels of FPN expression, causing an accumulation of intracellular iron and eventually resulting in iron-induced cell death ( 3.5 Ferroptosis in lymphocytes Lymphocytes represent the smallest category of white blood cells

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After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)

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