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Defective p53 activity is increasingly implicated in the etiology of several additional uncommon genetic disorders, such as DiamondBlackfan anemia (DBA), CHARGE syndrome, and ATR-Seckel syndrome

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The liver is the primary site of detoxification and requires high concentrations of both substances to function optimally

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doi: 10.1097/IOP.0000000000000037 64 SistiECocoBMenconiFLeoMRocchiRLatrofaFet al