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Physiologically based pharmacokinetic (PBPK) models have been developed for exenatide (1 of 30), dulaglutide (1 of 30), semaglutide (1 of 30), and tirzepatide (2 of 30)

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As the incretin effect of GLP-1 is greatly responsible for the insulin secretion after an oral glucose load, we determined the GLP-1 levels after the oral glucose challenge

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