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In principle, these distinct entry points could produce additive AMPK activation, but this dual activation has not been formally studied in humans and warrants physician oversight, particularly regarding blood glucose monitoring

322 reported that SSRIDDS is also associated with mutations in BICRA (BRD4 interacting chromatin remodeling complex-associated protein) gene

IV fluids, electrolyte correction Antiemetics Consider holding the GLP-1 agent NG decompression if severe 2

Ethics declarations Conflicts of interest The authors have no conflicts of interest relevant to this study to disclose

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CBS and CSE have been reported to re-localise to mitochondria in response to hypoxia, a common feature of the tumour microenvironment, resulting in targeted H 2 S delivery that can stimulate ATP production and protect mitochondria from oxidative stress