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Clinical studies rhGH treatment Three-day administration of rhGH at dosages comparable to those used for uremic growth failure did not increase GFR in adult CKD patients with a median baseline GFR of 21 ml/min/1.73 m 2 , despite significant anabolic effects with respect to serum cholesterol levels and urea excretion rates [33]., Tnshoff et al

For APOE4 carriers specificallywho show accelerated mitochondrial dysfunctionthis pathway represents a mechanistically rational intervention target

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