Moreover, weight cycling has previously been associated with lower muscle mass and strength, as well as an increased risk of SO [99, 100]
dose reduction of these concomitant agents is often necessary Thyroid C-cell tumors : Based on rodent studies, GLP-1 receptor agonists carry a boxed warning regarding medullary thyroid carcinoma risk and are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 Intestinal obstruction/ileus : Rare cases have been reported with some agents
5.4 Mood and Sleep Disorders Phentermine and topiramate extended-release capsules can cause mood disorders, including depression and anxiety, as well as insomnia
Effect of L-carnitine on weight loss in adults: systematic review and meta-analysis
Boucher TJ, Okuse K, Bennett DL, et al
Additionally, elderly patients and those with multiple comorbidities may be more vulnerable to dehydration and electrolyte disturbances from gastrointestinal side effects