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Tras la administracin intravenosa directa de glucosa a pacientes con DM2, la semaglutida, en comparacin con el placebo, mejor la primera y la segunda fase de la respuesta insulnica con un aumento del triple y el doble, respectivamente, y aument la actividad secretora mxima de las clulas beta pancreticas tras el ensayo de estimulacin con arginina